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Proteomics (Shigeo Hayashi)
 

 
Akira Nakamura Ph.D.

Mass Spectrometry Analysis Unit (Akira Nakamura)

Research Areas

The identification of the individual components of molecular complexes and elucidation of their structures can provide fundamental insights into the intricate mechanisms of development and regeneration. The Mass Spectrometry Analysis subunit uses LC-MASS spectrometry, a technology that enables the high-speed analysis of protein components from even minute biological samples. The subunit undertakes the analysis of protein modifications as well.


Select references

Otani T, et al. IKKe regulates cell elongation through recycling endosome shuttling Dev. Cell 20.219-32 (2011)

Hayakawa T, et al. MRG15 binds directly to PALB2 and stimulates homology-directed repair of chromosomal breaks. J Cell Sci 123.1124-30 (2010)

Shirai A, et al. Methylation of ribosomal protein L42 regulates ribosomal function and stress-adapted cell growth. J Biol Chem 285.22448-60 (2010)

Terasawa M, et al. Caenorhabditis elegans ortholog of the p24/p22 subunit, DNC-3, is essential for the formation of the dynactin complex by bridging DNC-1/p150(Glued) and DNC-2/dynamitin. Genes Cells 15.1145-57 (2010)